Vaccines This preprint from India found that a nasally-administered adenovirus-vectored vaccine gave mice good protection against BQ.1.1 and XBB.1.5. This preprint from China found that in mice, one Omicron booster after two COVID Classic vaccinations wasn’t as effective as one would like due to imprinting on COVID Classic (aka “original antigenic sin”). The good news… Continue reading 2023-05-21 General small
Category: Mitigation Measures
2023-05-04 General
I had an ugly thought. Maybe it makes a certain sense from the majority’s standpoint, to remove all restrictions because it would level the playing field. If COVID-19 does cause lasting damage, e.g. in increasing the risk of death or disability, then the people who have never had COVID-19 have an advantage over the people… Continue reading 2023-05-04 General
2023-04-20 General
Folks, we have a problem. We have a problem with language. When I say “Long COVID”, you probably immediately think “brain fog and/or fatigue” (and maybe you’ll think of a persistent cough and/or loss of smell/taste). What you probably do not think of is a higher chance of severe illness/death from something that doesn’t look… Continue reading 2023-04-20 General
2023-04-06 General
Transmission It is pretty clear to me that COVID-19 spread is airborne — there has been lots of evidence in the literature for that — but I had not seen any evidence that it spread via surface contact (fomites). This paper from the UK makes a strong case for fomites being important. They tracked household… Continue reading 2023-04-06 General
2023-03-16 General
Many people mark 11 March 2020 as the day “shit got real” with COVID-19. That was the day that Tom Hanks announced that he’d gotten COVID-19 and the NBA shut down. To mark the anniversary, there were a ton of three-year retrospectives this week, and there apparently was a Canadian National Day of Observance (which… Continue reading 2023-03-16 General
2023-03-09 General
I feel like I haven’t done as much research this week, but I’m just flat too tired today to do more. I will probably make tomorrow’s “tiny” posting beefier. There’s also supposed to be a press conference tomorrow; I plan to watch that and report on it. Vaccines Per this Statement, NACI recommends that vulnerable… Continue reading 2023-03-09 General
2023-03-02 General
Health Care System This article says that federal Health Minister Jean-Yves Duclos intervened in November with Canada’s drug price regulator to drop a policy reform process. 😠😬 Mitigation Measures This article (drawing from information in a number of papers) says that early targeted border closures were ineffective. (Basically, shutting down flights from South Africa and… Continue reading 2023-03-02 General
2023-02-02 General
Vaccines It’s here! This preprint from India has the first data for nasal vaccines in humans that we’ve seen. It compares of the same inactivated adenovirus delivered nasally (BBV154) and intramuscularly (Covaxin), both from Bharat Biotech: Levels of antibodies and good things range from about 1.5x to almost 2x higher when delivered nasally. There were… Continue reading 2023-02-02 General
2023-01-26 General
Vaccines People ask me which vaccine they should get. I tell them it’s really between the Pfizer BA.4/5 bivalent and the Novavax, that I don’t have enough information to distinguish between those two. This paper from Novavax with data from South Africa says that three doses of Novavax works about as well as — not… Continue reading 2023-01-26 General
2023-01-12 General
Mitigation Measures This article says that the US has put in a new rule that air travellers must be fully vaccinated before getting on a plane to the US. (Confirmed at this US CDC page.) This paper from Ontario (from August) found that parents, in addition to everything else they were dealing with, had a… Continue reading 2023-01-12 General