2023-12-01 General

Long COVID This preprint from USA (2023-11-08) discussed a small study with 16 Long COVID patients who had small fiber neuropathy verified by skin biopsies. Eight of the patients got intravenous immunoglobulin and saw big improvements. This paper from Pakistan (20231122) found that people who were fully vaccinated were 62% less likely to get Long… Continue reading 2023-12-01 General

2023-11-25 General

Pathology This paper from USA says that 48.5% of people hospitalized with COVID-related fungal infections died, while only 12.3% of people hospitalized with non-COVID-associated fungal infections died. This paper from Taiwan found that people who got COVID-19 infections were 59% more likely to get shingles in the following year than controls. This report from Korea… Continue reading 2023-11-25 General

2023-05-21 General small

Vaccines This preprint from India found that a nasally-administered adenovirus-vectored vaccine gave mice good protection against BQ.1.1 and XBB.1.5. This preprint from China found that in mice, one Omicron booster after two COVID Classic vaccinations wasn’t as effective as one would like due to imprinting on COVID Classic (aka “original antigenic sin”). The good news… Continue reading 2023-05-21 General small

2023-05-04 General

I had an ugly thought. Maybe it makes a certain sense from the majority’s standpoint, to remove all restrictions because it would level the playing field. If COVID-19 does cause lasting damage, e.g. in increasing the risk of death or disability, then the people who have never had COVID-19 have an advantage over the people… Continue reading 2023-05-04 General

2023-04-20 General

Folks, we have a problem. We have a problem with language. When I say “Long COVID”, you probably immediately think “brain fog and/or fatigue” (and maybe you’ll think of a persistent cough and/or loss of smell/taste). What you probably do not think of is a higher chance of severe illness/death from something that doesn’t look… Continue reading 2023-04-20 General

2023-04-06 General

Transmission It is pretty clear to me that COVID-19 spread is airborne — there has been lots of evidence in the literature for that — but I had not seen any evidence that it spread via surface contact (fomites). This paper from the UK makes a strong case for fomites being important. They tracked household… Continue reading 2023-04-06 General