2021-10-14 General

Vaccines Someone is live-tweeting the La Jolla Immunology Conference, and during a panel about an important paper from May that I’ve already talked about, they said something which I missed: that inter-individual variations in antibody responses are larger than the variations between responses to different variants. I’ve talked about the two-proline (2P) and six-proline (6P)… Continue reading 2021-10-14 General

2021-10-13 General

Diagnosis / Equity This Twitter thread suggests that the reason darker-skinned people have higher fatality rates from COVID-19 is because, well, they have darker skin: pulse oximeters, which are used to judge how serious a case is, don’t work on dark-skinned people. Economic effects This video from January 2021 makes the economic case — not… Continue reading 2021-10-13 General

2010-10-09/10/11/12 General

Mitigation Measures This article says that the US will allow fully-vaccinated Canadians to enter, starting sometime in November. “Fully-vaccinated” has not been clearly defined yet. Vaccines Novavax has published data from their Phase 3 trials in the USA and Mexico in this preprint. I wanted to be snarky and say that maybe this means that… Continue reading 2010-10-09/10/11/12 General

2021-09-29 General

Testing/Diagnostics In this study, they put a wristwatch-like thing on the wrists of people who willingly allowed themselves to be infected with either rhinovirus, flu, or placebo. The wristwatch thingie was able to predict illness about a day before symptoms showed up. This could be really useful for diagnosing other respiratory infections (like ahem COVID-19).… Continue reading 2021-09-29 General

2021-09-15 General

Vaccines I mentioned a study from England yesterday which looked at waning immunity. This tweet thread looks more closely, and there’s good stuff in the report that I missed. First, here’s the original study. Yes, it looks you’ve got a significant loss in effectiveness against infection if you look at the over-sixteens, but if you… Continue reading 2021-09-15 General

2021-09-14 General

Vaccines This article has a graph of AZ and Pfizer’s effectiveness over time for old folks. It’s not pretty (but remember that they used a short dose interval, and Canada mostly used a long interval). Even for younger people, it’s not great news: This preprint says that people who have a spare tire around their… Continue reading 2021-09-14 General

2021-09-11/12/13 General

Transmission This report says that seroprevalence of COVID-19 antibodies from infection in Canadian blood donors went up to 4.5%, up from 4.0% in May. (How can they tell the difference? Vaccines only make antibodies to the spike protein, so if there are antibodies to some other part of the SARS-CoV-2 virus, then it was acquired… Continue reading 2021-09-11/12/13 General