2021-10-23/24/25 General

Transmission In this small study of Italian health-care workers who were tested regularly, all of the people who tested positive but were asymptomatic tested negative the very next day. The mean time for the symptomatic patients to test negative was 11 days. Pathology This preprint says they found SARS-CoV-2 antibodies in the cerebrospinal fluid of… Continue reading 2021-10-23/24/25 General

2021-10-22 General

Vaccines This article reports that pediatric Pfizer is 90.7% effective against infection in children. Long COVID This preprint says that various forms of cognitive impairment are pretty common several months after “getting over” COVID-19. People who went the ER are more likely to have cognitive impairment than people who were treated as outpatients. Recommended Reading… Continue reading 2021-10-22 General

2021-10-21 General

Mitigation Measures This article talks about $7.4B in relief spending that the Government of Canada has announced. All three of these programs will go until 7 May 2022. Canada Recovery Benefit (CRB) will be replaced by the Canada Worker Lockdown Benefit and will provide $300 a week to eligible people. The Tourism and Hospitality Recovery… Continue reading 2021-10-21 General

2021-10-19 General

Vaccines This preprint is yet another study showing that infection+vaccination gives a stronger and more durable response that vaccination alone or infection alone. There have been so many studies showing that result that I am getting tired and bored with them, and probably will not post any more. This preprint about vaccines and pregnancy found:… Continue reading 2021-10-19 General

2021-10-14 General

Vaccines Someone is live-tweeting the La Jolla Immunology Conference, and during a panel about an important paper from May that I’ve already talked about, they said something which I missed: that inter-individual variations in antibody responses are larger than the variations between responses to different variants. I’ve talked about the two-proline (2P) and six-proline (6P)… Continue reading 2021-10-14 General

2021-10-13 General

Diagnosis / Equity This Twitter thread suggests that the reason darker-skinned people have higher fatality rates from COVID-19 is because, well, they have darker skin: pulse oximeters, which are used to judge how serious a case is, don’t work on dark-skinned people. Economic effects This video from January 2021 makes the economic case — not… Continue reading 2021-10-13 General

2010-10-09/10/11/12 General

Mitigation Measures This article says that the US will allow fully-vaccinated Canadians to enter, starting sometime in November. “Fully-vaccinated” has not been clearly defined yet. Vaccines Novavax has published data from their Phase 3 trials in the USA and Mexico in this preprint. I wanted to be snarky and say that maybe this means that… Continue reading 2010-10-09/10/11/12 General

2021-10-07 General

Long COVID This study from the UK found: there were subtle differences in T cells which correlated strongly (but not perfectly) with having Long COVID; giving histamine receptor antagonists made 72% of them better (!!!); something which the histamine receptor antagonists never helped was dysautonomia, which suggests that there is some different mechanism causing that.… Continue reading 2021-10-07 General