Happy New Year! Measures In the USA, the US CDC decided that five days was enough time to isolate. Per this tweet, five days later, the number of COVID-19 transmissions in hospitals went up: In BC, we just dropped to five-day isolation (as long as you have no symptoms). It would be interesting to see… Continue reading 2022-01-01/02/03/04 General
Category: Long COVID
2021-12-25/26/27/28 General
Variants There has been difficulty figuring out how badly Omicron is going to hit the hospital system first because it is a lagging indicator, second because Omicron affects vaccinated and unvaccinated people so differently, and third because of poor-quality data around the holidays. Still, there are hints that, as this tweet from New York says,… Continue reading 2021-12-25/26/27/28 General
2021-12-11/12/13 General
Testing This report says that rapid tests are really inaccurate (they compared to PCR). This Twitter thread summarizes, but the brand I just picked up in the US misses half of symptomatic cases and a quarter of asymptomatic cases. (They say you should test multiple times, which if the failures are randomly distributed, should drop… Continue reading 2021-12-11/12/13 General
2021-11-23 General
Mitigation Measures I have heard that it is critically important for masks to fit well to be useful, yet most of the people I see wearing masks have big obvious gaps in them. How could these possibly work? And yet, clearly they do. In addition to multiple studies showing mask-wearing reduces cases, pretty much every… Continue reading 2021-11-23 General
2021-11-20/21/22 General
Pathology This article says that people with mental illnesses are at much higher risk of COVID-19 infection, hospitalization, and death. I gather that it’s not the mental illness per se, but the consequences of mental illness that put them at risk. Mitigation Measures This article reports that the Government of Canada has ended its COVID-era… Continue reading 2021-11-20/21/22 General
2021-11-16 General
Long COVID This preprint says that they found a chemical signature (elevated IL-1ß, IL-6 and TNF-α) associated with Long COVID. This is good for two reasons: it can help “prove” to doctors that the patients really have Long COVID and aren’t just lazy and it can suggest what the problem is and hence how to… Continue reading 2021-11-16 General
2021-11-04 General
Genetics This preprint talks about using virus-like particles to study viruses. It looks enough like SARS-CoV-2 that it can get into cells, but then it can’t replicate. Essentially, it’s shooting blanks. This study identified a specific gene variant (which comes from Neanderthals!) which gives a 2x risk of respiratory failure. About 60% of people of… Continue reading 2021-11-04 General
2021-10-30 to 11-01 General
Vaccines This preprint from Israel says that the vaccine effectiveness of a third dose of Pfizer vs. two doses of Pfizer at least five months ago was: 93% against hospitalization, 92% against severe disease (which I think is equivalent to “ICU” here), 81% against death. This article says that Novavax has finished its rolling review… Continue reading 2021-10-30 to 11-01 General
2021-10-28 General
Treatment This paper says that a single infusion of a new-to-me polyclonal antibody — sotrovimab — is 85% effective at preventing hospitalization when given early to high-risk COVID-19 patients. The FDA already gave an EUA to sotrovimab on 26 May; Canada gave interim approval on 30 July (and bought 10,000 doses on 4 October), so… Continue reading 2021-10-28 General
2021-10-27 General
Treatments Yay! This article says that Merck has licensed molnupiravir such that ~100 developing countries can manufacture it at low cost! This is awesome. (It hasn’t been approved by any countries yet, but it will be soon, I’m sure.) Yay yay! This article reports that a cheap mature drug for depression — fluvoxamine — reduces… Continue reading 2021-10-27 General