Vaccines This large study from Scotland from March 2020 to November 2020 found that household members of healthcare workers were less than half as likely to get an infection after the healthcare worker got vaccinated. (Note: don’t forget that some of the household members got infected in the community.) This study of Pfizer found that:… Continue reading 2021-09-08 General
Category: Treatments
2021-09-01 General
Treatments Good news! This preprint says that baricitinib reduces all-causes mortality of hospitalized COVID-19 patients by 38.2%! Vaccines Remember how I was saying that I thought we’d see that longer doses were better? It turns out that waaay longer is better. This preprint says that for AstraZeneca, antibody levels were four times higher in people… Continue reading 2021-09-01 General
2021-08-21/22 General
Transmission This great preprint of healthcare workers in the Netherlands finds that despite having similar PCR results for vaccinated and unvaccinated people, vaccinated people actually are less likely to have actual infectious viruses. PCR tests look for pieces of RNA, but the RNA might be fragments, it’s not necessarily whole virus which can cause infection.… Continue reading 2021-08-21/22 General
2021-08-20 General
Mitigation Measures This article says that masking was responsible for a 68% reduction in transmissions and that regular testing got the reduction up to 77%. This preprint looked at different mitigation measures in schools in Switzerland. Some highlights of the reductions in viral dosage they saw: Keeping all the windows open in winter: 14x Universal… Continue reading 2021-08-20 General
2021-08-18 General
Vaccines There has been a lot of discussing recently about waning effectiveness of vaccines. I want to editorialize for a moment: you expect vaccine effectiveness against infection to appear worse in real life than in the studies, and to appear worse over time. More time to get infected. If the vaccine is 95% effective over… Continue reading 2021-08-18 General
2021-08-04 General
Treatments This preprint says that injecting REGEN-COV (a monoclonal antibody treatment that you might know by the name of the company, Regeneron) into people who have been exposed to COVID-19 prevents developing a symptomatic infection with efficacy of 92.6%. This is a BFD. Before, they had to give it as an infusion i.e. the patients… Continue reading 2021-08-04 General
2021-07-20 General
Vaccines This article had this stunning graphic of the difference in mortality in the UK due to vaccines: This article reports that vaccines might re-activate dormant chickenpox, leading to shingles. If you are over 50, get a shingles shot! Mitigation Measures This article says that some restrictions in long-term care homes have been lifted. Visits… Continue reading 2021-07-20 General
2021-07-14 General
Vaccines This study shows that Pfizer gives really good protection to pregnant women (66%/97% against symptomatic infection with one/two doses). This small study (129 participants) from Hannover, Germany and this other even smaller study (59 participants) from Kiel Germany, showed that in test tubes, AZ+Pfizer is better than AZ+AZ (especially against Beta), and has basically… Continue reading 2021-07-14 General
2021-07-08 General
Vaccines Pfizer says that a third shot boosts antibody levels 5x to 10x against COVID Classic and Beta. Remember that antibodies aren’t the whole story, and that Pfizer has incentive to get as many people as possible to buy their vax. They also said they are working on a Delta-specific booster. The US FDA immediately… Continue reading 2021-07-08 General
2021-07-07 General
Vaccines A few days ago, there was a Israeli Ministry of Health report saying that Pfizer was only 64% effective against the Delta strain, which was far lower than other studies had found. It looks like the study in Israel was against all infection, including asymptomatic infection, while the others were against symptomatic infection. That… Continue reading 2021-07-07 General