Variants I have been frustrated with some of the talk around Omicron’s virulence, and this tweet made me realize what my problem was: we shouldn’t be talking about THE virulence (usually expressed as the Case Hospitalization Rate or CHR) as a single number. There is a different CHR for the general population (the observed virulence)… Continue reading 2021-12-23 General
Category: Treatments
2021-12-21 General
Variants More qualified good news: this preprint out of South Africa says that Omicron is only 70% as likely to send someone to the hospital as Delta. All the same caveats I’ve made previously apply, though. This Twitter thread does an estimate of the Case Hospitalization Rate (CHR) in New South Wales, Australia. This is… Continue reading 2021-12-21 General
2021-12-15 General
Mitigation Measures This article says that the federal government is advising against international travel. (If you go to the travel advisory page, for every country, it says you shouldn’t go there.) This article says that the Finance Minister Chrystia Freeland committed a whole bunch of money to fight COVID-19 . Variants There were a ton… Continue reading 2021-12-15 General
2021-12-14 General
Variants According to this Twitter thread, which reported on a press conference in South Africa, Omicron now accounts for 90% of the cases in South Africa. (Note: it might not be displacing Delta, there might still be just as many Delta cases as before — I don’t now — but a huge number of Omicron… Continue reading 2021-12-14 General
2021-12-08/09/10 General
I was out of town for a few days. I think this mostly catches up. Variants This press release from Pfizer says that three doses of Pfizer will give reasonable protection against infection with Omicron, but two doses isn’t enough. Two doses should still protect against severe disease. This Twitter thread on a report from… Continue reading 2021-12-08/09/10 General
2021-12-07 General
A lot of highly technical material dropped today, on a day when I was kind of busy, so I have not had enough time to really understand everything. AND information about Omicron is still in flux. So if you don’ t understand something here, it’s not just you. Also, there will probably not be postings… Continue reading 2021-12-07 General
2021-11-26 General
Variants This article talks about the race to contain B.1.1.529, now formally named Omicron (not Nu). This article reports that Pfizer/BioNTech say that they will know in under two weeks how effective their vax is against Omicron, and that they can have a revamped shot done in 100 days. Moderna says they’ve been working on… Continue reading 2021-11-26 General
2021-11-18 General
Treatments This article talks about the good long-term results of AstraZeneca’s polyclonal antibody (brand name Evusheld). The article says it’s a two shot therapy like a vaccine, and given pre-exposure gives 83% protection over six months, sort of like a vaccine. Unlike a vaccine, however, it should work just as well in people who are… Continue reading 2021-11-18 General
2021-11-10 General
Treatments Okay, this preprint is wild — if I understand it correctly. My understanding is that the authors made a thing — a Therapeutic Interfering Particle or TIP — which looks just like SARS-CoV-2 except it has a vastly stripped-down genome, one that doesn’t have all the instructions needed to make the enzymes and proteins… Continue reading 2021-11-10 General
2021-11-05 General
Treatment Fantastic news! Pfizer has a pill which, if you take it in the first three days after symptoms appear, cuts hospitalization by NINETY F PERCENT!!! If taken within the first five days, it’s ~85% effective. The pill, called Paxlovid, is a protease inhibitor, which ought to be easy to make and have low side… Continue reading 2021-11-05 General