Vaccines This Twitter thread is an excellent discussion of how to understand the “do vaccines wane” discussion. Please go read it. The US FDA today gave full approval to Pfizer, as opposed to the Emergency Use Authorization that it had given. This is important because there were entities which were not legally able to require… Continue reading 2021-08-23 General
Category: General
2021-08-21/22 General
Transmission This great preprint of healthcare workers in the Netherlands finds that despite having similar PCR results for vaccinated and unvaccinated people, vaccinated people actually are less likely to have actual infectious viruses. PCR tests look for pieces of RNA, but the RNA might be fragments, it’s not necessarily whole virus which can cause infection.… Continue reading 2021-08-21/22 General
2021-08-20 General
Mitigation Measures This article says that masking was responsible for a 68% reduction in transmissions and that regular testing got the reduction up to 77%. This preprint looked at different mitigation measures in schools in Switzerland. Some highlights of the reductions in viral dosage they saw: Keeping all the windows open in winter: 14x Universal… Continue reading 2021-08-20 General
2021-08-19 General
Vaccines I see a lot of anxiety about vaccines decreasing in effectiveness. In the US, Biden announced that third-dose-boosters would start being delivered on 20 August, never mind that the FDA has not yet approved boosters. Here is an example of someone showing the waning effectiveness of the vaccines: But some of the studies have… Continue reading 2021-08-19 General
2021-08-18 General
Vaccines There has been a lot of discussing recently about waning effectiveness of vaccines. I want to editorialize for a moment: you expect vaccine effectiveness against infection to appear worse in real life than in the studies, and to appear worse over time. More time to get infected. If the vaccine is 95% effective over… Continue reading 2021-08-18 General
2021-08-17 General
Variants This article talks about a lot of things, but says: Breakthrough cases appear to be increasing for Delta. However, they don’t give any “before” numbers, and it’s not clear if it’s just because the number of vaccinated people is increasing. The absolute number of breakthrough cases is still low. The average age of a… Continue reading 2021-08-17 General
2021-08-16 General
Vaccines In this preprint, they found antibody levels post-vax were (slightly) higher in women, younger people, Moderna vaccinees (vs. Pfizer), people who had prior COVID-19, and those who had significant side-effects. If I understand this table correctly, you are more likely to have significant side effects after dose 1 if you were over 60, female,… Continue reading 2021-08-16 General
2021-08-14 General
Mitigation Measures Huh. This web page from the US CDC says that an N95 with an exhalation valve is as good or better at source control (i.e. protecting the people the wearer is close to) than a procedure mask (the standard medical hook-over-your-ears mask that you see unfortunately frequently see lying on the ground as… Continue reading 2021-08-14 General
2021-08-13 General
Hospitalizations An independent statistician pulled together this graph: Why does Quebec have such a fall-off in hospitalizations/confirmed case and ICU admissions/confirmed case when the other provinces do not? Because Quebec does a better job testing/finding cases, so the denominator is bigger. Note that the most recent data is excluded because the episode date is when… Continue reading 2021-08-13 General
2021-08-11/12 General
Testing Three dogs have been trained in Vancouver to sniff out COVID-19 with very high accuracy! Transmission Yow! This preprint says that 6.8% of COVID-19 patients in England caught it in the hospital. Vaccines Good news! Adolescents tolerated two doses of Moderna, and the vax arm had no cases vs. four in the placebo arm.… Continue reading 2021-08-11/12 General