Variants There continue to be studies in test tubes and lab rodents which all show pretty convincingly that Omicron does not infect the lungs as well as previous versions. This preprint says that T cells from vaccination still have 70-80% of their protection against Omicron (which is probably why breakthrough cases are mild). Transmission This… Continue reading 2021-12-29 General
Category: General
2021-12-25/26/27/28 General
Variants There has been difficulty figuring out how badly Omicron is going to hit the hospital system first because it is a lagging indicator, second because Omicron affects vaccinated and unvaccinated people so differently, and third because of poor-quality data around the holidays. Still, there are hints that, as this tweet from New York says,… Continue reading 2021-12-25/26/27/28 General
2021-12-24 General
This is short because Happy Christmas Eve! Testing This paper from October says that there is 1.7x variation in PCR test results over the course of a day, with 2pm being the time when an infected person will have the highest viral load. This article says that it’s not legal for you to redistribute rapid… Continue reading 2021-12-24 General
2021-12-23 General
Variants I have been frustrated with some of the talk around Omicron’s virulence, and this tweet made me realize what my problem was: we shouldn’t be talking about THE virulence (usually expressed as the Case Hospitalization Rate or CHR) as a single number. There is a different CHR for the general population (the observed virulence)… Continue reading 2021-12-23 General
2021-12-22 BC/General
I am going to take the rest of the day off as a mental health break. Brief bits from what I have already seen: UK had 100K cases yesterday, which sounds like an unimaginatively huge number until you realize that’s ~6K cases/day when adjusted for the different population — which is only two doublings from… Continue reading 2021-12-22 BC/General
2021-12-21 General
Variants More qualified good news: this preprint out of South Africa says that Omicron is only 70% as likely to send someone to the hospital as Delta. All the same caveats I’ve made previously apply, though. This Twitter thread does an estimate of the Case Hospitalization Rate (CHR) in New South Wales, Australia. This is… Continue reading 2021-12-21 General
2021-12-18 General
I knew this was coming. I knew this was coming. I knew this would be bad. I predicted that the health care system might collapse in multiple jurisdictions in the West. I’m still somewhat shocked at the ferocity and this wave. There are lots of people saying that Omicron is milder than previous variants (see… Continue reading 2021-12-18 General
2021-12-17 General
I remember thinking it was really strange that more people died in the second year of the Spanish Flu pandemic than the first. I’m not surprised any more. Vaccines Someone asked me today, “would Omicron still have arisen if we’d had equitable and effective vaccine distribution globally? At first I hedged, and said we couldn’t… Continue reading 2021-12-17 General
2021-12-16 General
I’m tired and kind of depressed. I (and many other people) saw Omicron coming weeks ago, and now it’s here. It’s just as bad as I feared, and perhaps even worse. 🙁 Omicron is dominating the news, but … it’s not really news. There’s a lot of people saying “OH SHIT! WE ARE FUCKED!”, but… Continue reading 2021-12-16 General
2021-12-15 General
Mitigation Measures This article says that the federal government is advising against international travel. (If you go to the travel advisory page, for every country, it says you shouldn’t go there.) This article says that the Finance Minister Chrystia Freeland committed a whole bunch of money to fight COVID-19 . Variants There were a ton… Continue reading 2021-12-15 General