Vaccines This paper says that there is a blood-olfactory barrier (similar to the blood-brain barrier) and that blood-borne antibodies can’t get to the olfactory epithelium (mucous membrane lining). (Note that SARS-CoV-2 can get to the brain via the olfactory bulb. !!) That suggests that we are never going to get to sterilizing immunity (i.e. you… Continue reading week ending 2022-09-22 General
Category: Transmission
week ending 2022-09-15 General
Pathology This paper from the USA says that what gut microbes you have affects how badly COVD-19 hits you. (That’s a slight simplification — they looked at population-level frequency of various gut bacteria and compared it to population-level hospitalization rate.) This article from July 2020 says that the amount of fermented food that people eat… Continue reading week ending 2022-09-15 General
week ending 2022-09-08 General
Unwanted Side Effects This paper from Paris found that, while infant head trauma (which is usually caused by child abuse) did not go up in 2020, it doubled in 2021. 😬 Vaccines Good news on the mucosal antibodies front! (Reminder: you want antibodies in the mucous because COVID-19 hits the mucous membranes of the respiratory… Continue reading week ending 2022-09-08 General
week ending 2022-08-18 General
Live Attenuated Virus Vaccines This paper from Massachusetts found that vaccination with the tuberculosis BCG vaccine gave a 92% efficacy against COVID-19. (Also see this mass media article, which talks about other studies too.) BCG is a live attenuated virus vaccine (LAV); I’ve talked about LAVs before and how they appear to boost the innate… Continue reading week ending 2022-08-18 General
week ending 2022-07-28 General
Transmission Here’s another preprint (from the UK) which says that the “you don’t have to isolate longer than five days” guidance is bullshit. It says that the median person was infectious — even if asymptomatic — for 7 to ten days. This paper from the USA found that while adults who were not exposed to… Continue reading week ending 2022-07-28 General
week ending 2022-07-14 General
Vaccines This article reports that Moderna has been approved in Canada for kiddies between six months and five years old. This article reports that an Alberta judge ruled that it was okay to require transplant patients to get a COVID vax, given the scarcity of organs and the much higher likelihood that unvaxxed organ recipients… Continue reading week ending 2022-07-14 General
week ending 2022-06-30 General
Folks, BA.5 is coming and it’s going to be bad. Mentally prepare yourself for a big wave this summer. I don’t know where to put it, but this paper says that compared to peer countries, Canada: Did really well on per capita vaccinated, cases, and deaths. (You could argue that we’re fudging the numbers, but… Continue reading week ending 2022-06-30 General
week ending 2022-06-23 General
Sorry this was late. Life happened. Pathology This article summarizes this paper which says that the chances of bad COVID outcomes are cumulative with exposures. Getting COVID-19 twice is worse than once, three times is worse than two, etc. (Here’s a blog post which talks about this paper more.) As you can see, you are… Continue reading week ending 2022-06-23 General
week ending 2022-06-16 General
Long COVID This article about Long COVID in the US is interesting. It says that a lot of the indicators which you would expect to see Long COVID shift (e.g. number of disability claims, health care expenditures), have not in fact shifted. The article gives a number of possiblities: A lot of disabled people died… Continue reading week ending 2022-06-16 General
week ending 2022-06-02 General
Long COVID I was puzzled for a long time: all the statistics I saw said that Long COVID was really common — from 5% to 50%, depending on which study you looked at — but I didn’t know anybody with Long COVID! How could this be? I thought maybe it was because my echo chamber… Continue reading week ending 2022-06-02 General