Variants This is really strange. This article says that in New York City and also in some places in California, they have been seeing strange variants in their wastewater surveillance for the past year — variants they haven’t seen in any people. It wasn’t clear, but I think there are three main lineages (classed as… Continue reading 2022-02-03 General
Category: General
2022-02-02 General
Happy Twosday! Transmission This article reports on the results of the first human challenge trial (meaning: deliberate infection) of COVID Classic. You’re going WAIT WHAT? HOW COULD THAT POSSIBLY PASS ETHICS REVIEW? This happened in the UK (so different ethics boards), and they did work hard to minimize potential harm to the subjects (like making… Continue reading 2022-02-02 General
2022-02-01 General
Vaccines This study in Israel of people over 60 found that the risk of infection dropped in half after their fourth dose of vaccine; the risk of severe illness dropped by a fourth. Note that this sounds really good, but the study was only in people over 60, and there’s no information on waning. Pathology… Continue reading 2022-02-01 General
2022-01-29/30/31 General
Vaccines There’s a great, long Twitter thread which looks at the effect of vaccines. (It summarizes a paywalled article, if you want to see the whole thing.) One of the elements which I found striking was how the risk of COVID-19 relative to the flu has dropped over time. In mid 2020, the infection fatality… Continue reading 2022-01-29/30/31 General
2022-01-31 Booster Recommendation
I am putting this here in a stand-alone document so that I can refer to it easily. People have been asking me which booster they should get, Pfizer or Moderna? For effectiveness, the answer is always Moderna, though it’s not so bad if you get Pfizer. All the studies I have seen say that Moderna… Continue reading 2022-01-31 Booster Recommendation
2022-01-28 General
Variants I don’t like to warn about variants before there’s data. (I didn’t sound alarms about Mu, for example.) Well, I think it’s time to talk about BA.2 — an Omicron variant. (The Omicron variant which sprouted up first is BA.1.) BA.2 doesn’t look like it is lot worse than BA.1 — not like Delta… Continue reading 2022-01-28 General
2022-01-27 General
Pathology This study found that pregnant women were 1.77x as likely to develop preeclampsia if they got COVID-19; women who had not given birth before were 1.89x as likely. They found the risk of a preterm birth for all pregnant women with both COVID-19 and preeclampsia was 4.05x (and 6.26x for women who had never… Continue reading 2022-01-27 General
2022-01-26 General
Mitigation Measures This preprint looked at high-risk exposures and said that the risk of catching COVID-19 was: 3.02x higher if the infected person was part of your household (versus not), 2.1x higher if the transmission was indoors (versus outdoors), 2.15x higher if the interaction lasted 3 hrs or more (vs. shorter) among unvaccinated and partially-vaccinated… Continue reading 2022-01-26 General
2022-01-25 General
Long COVID This preprint says that they found four predictors which are strongly correlated with Long COVID: type 2 diabetes, SARS-CoV-2 RNA in the blood, Epstein-Barr virus in the blood, and specific autoantibodies. (Here’s an article translating the subject into lay-speak. Paywalled, sorry.) This paper also found a Long COVID signature/diagnostic, this time in age,… Continue reading 2022-01-25 General
2022-01-22/23/24 General
Weather This article says that the amount of lightning decreased during the pandemic because of less fossil fuel burning and hence fewer aerosols. Vaccines This article says that in extremely rare circumstances, people report Long COVID symptoms after vaccination. Variants This preprint says that the risk of hospitalization from Omicron is 25% that of Delta,… Continue reading 2022-01-22/23/24 General