2021-03-06 General

Treatments Fluvoxamine — an old anti-depressant — is being tested as a treatment for COVID. VOCs Yet another paper says that our vaccines (in this case, Moderna and Novavax) work against B.1.1.7.

2021-03-04 General

Vaccines Canada is probably going to approve the Johnson and Johnson COVID-19 vaccine in the next few days. That will make four vaccines, five if you count the Serum Institute of India’s vaccine as different from AstraZeneca. There is an article in the Economist which says that the differences in reported vaccine efficacy is really… Continue reading 2021-03-04 General

2021-03-03 General

Vaccines The Novavax vaccine — which had ~90% efficacy against B.1.1.7 — had only 60% efficacy against HIV-negative patients, most of whom had B.1.351. As a side effect, the study showed that having had COVID Classic didn’t give you any protection against B.1.351. Yikes. There is a report that, while rare, some delayed (5 days… Continue reading 2021-03-03 General

2021-03-02 General

Variants The New York Times has an article talking about the naming of variants. Basically, it’s hard to make strain names memorable while also avoiding place names, people’s names, and names of animals. 🙁 There are a few ways that scientists figure out how resistant a variant is to a vaccine. One is to look… Continue reading 2021-03-02 General

2021-03-01 General

Vaccines An article in the New York Times reports on studies which show that one dose of the AstraZeneca vaccine gives good protection. An article in the Washington Post says that the Israeli vaccine rollout — which has now reached 50% of its citizens and almost 90 percent of people over 50 — shows that… Continue reading 2021-03-01 General

2021-02-28 General

Long COVID There is a good thread by Dr. Iwasaki, a prominent virologist, suggesting possible mechanisms for Long-COVID and a clever vaccine trial which could help shed light on which mechanism it is. The possibilities she lists are: A persistent viral reservoir, i.e. the virus is hiding somewhere (like maybe the Central Nervous System) Inactive… Continue reading 2021-02-28 General

2021-02-26 General

Vaccines Canada approved the AstraZeneca vaccine and a version made in India! This is good news. Canada has ordered 20M doses from AstraZeneca and 2M from Serum Institute of India (which makes the AZ under license), 500,000 doses of which are supposed to arrive on Wednesday 3 March. I have heard people grumbling that they… Continue reading 2021-02-26 General

2021-02-25 General

Vaccines Great news! Moderna has vaccines against B.1.351 ready to for Phase 1 trials! They are going to do a test with three different arms, with two shots of the COVID Classic (as normal) and then a half dose of either: a vax against B.1.351 and only B.1.351, a vax that’s a mixture of the… Continue reading 2021-02-25 General

Vaccine effectiveness

Over the past two weeks, there have been quite a few studies which have shown that the vaccines work as expected. For example, see: The Economist — “the Pfizer-BioNTech vaccine reduced the hospitalisation rate among inoculated Scots by 85% four weeks after their first dose; the AstraZeneca-Oxford vaccine lowered hospitalisations by 94%. (The variation between… Continue reading Vaccine effectiveness